Regulator rasta estrogenom u raku dojke je protein koji je kod ljudi kodiran genom GREB1L.
Dužina polipeptidnog lanca u proteinu je 1.923 aminokiseline, а molekulska masa — 214.354.
Aminokiselinska sekvenca Simboli
C: Cistein D: Asparaginska kiselina E: Glutaminska kiselina F: Fenilalanin G: Glicin H: Histidin I: Izoleucin K: Lizin L: Leucin M: Metionin N: Asparagin P: Prolin Q: Glutamin R: Arginin S: Serin T: Treonin V: Valin W: Triptofan Y: Tirozin
1020304050 MGNSYAGQLKSARFEEALHNSIEASLRCSSVVPRPIFSQLYLDPDQHPFS SADVKPKVEDLDKDLVNRYTQNGSLDFSNNLTVNEMEDDEDDEEMSDSNS PPIPYSQKPAPEGSCTTDGFCQAGKDLRLVSLCMEQIDIPAGFLLVGAKS PNLPEHILVCAVDKRFLPDDHGKNALLGFSGNCIGCGERGFRYFTEFSNH INLKLTTQPKKQKHLKYYLVRSSQGVLSKGPLICWKECRSRQSSASCHSI KPSSSVSSTVTPENGTTNGYKSGFTQTDAANGNSSHGGKGSASSSTPAHT GNYSLSPRPSYASGDQATMFISGPPKKRHRGWYPGSPLPQPGLVVPVPTV RPLSRTEPLLSAPVPQTPLTGILQPRPIPAGETVIVPENLLSNSGVRPVI LIGYGTLPYFYGNVGDIVVSPLLVNCYKIPQLENKDLEKLGLTGSQFLSV ENMILLTIQYLVRLGPDQVPLREEFEQIMLKAMQEFTLRERALQIGAQCV PVSPGQLPWLARLIASVSQDLVHVVVTQNSLAEGISETLRTLSEMRHYQR LPDYVVVICASKIRGNEFCVVVLGQHQSRALAESMLTTSEFLKEISYELI TGKVSFLASHFKTTSLGDDLDKLLEKMQQRRGDSVVTPFDGDLNECVSPQ EAAAMIPTQNLDLDNETFHIYQPQLTVARKLLSQVCAIADSGSQSLDLGH FSKVDFIIIVPRSEVLVQQTLQRIRQSGVLVDLGLEENGTAHQRAEKYVV RLDNEIQTKFEVFMRRVKQNPYTLFVLVHDNSHVELTSVISGSLSHSEPS HGLADRVINCREVLEAFNLLVLQVSSFPYTLQTQQSRISSSNEVHWIQLD TGEDVGCEEKLYFGLSEYSKSLQWGITSPLLRCDETFEKMVNTLLERYPR LHSMVVRCYLLIQQYSEALMALTTMASLRDHSTPETLSIMDDLISSPGKN KSGRGHMLIIRVPSVQLAMLAKERLQEVRDKLGLQYRFEIILGNPATELS VATHFVARLKSWRGNEPEEWIPRTYQDLDGLPCIVILTGKDPLGETFPRS LKYCDLRLIDSSYLTRTALEQEVGLACCYVSKEVIRGPTVALDLSGKEQE RAAVSENDSDELLIDLERPQSNSSAVTGTSGSIMENGVSSSSTADKSQKQ SLTPSFQSPATSLGLDEGVSASSAGAGAGETLKQECDSLGPQMASSTTSK PSSSSSGPRTLPWPGQPIRGCRGPQAALPPVVILSKAAYSLLGSQKSGKL PSSSSLLPHADVAWVSSLRPLLNKDMSSEEQSLYYRQWTLARQHHADYSN QLDPASGTRNFHPRRLLLTGPPQVGKTGSYLQFLRILFRMLIRLLEVDVY DEEEINTDHNESSEVSQSEGEPWPDIESFSKMPFDVSVHDPKYSLMSLVY TEKLAGVKQEVIKESKVEEPRKRETVSIMLTKYAAYNTFHHCEQCRQYMD FTSASQMSDSTLHAFTFSSSMLGEEVQLYFIIPKSKESHFVFSKQGKHLE SMRLPLVSDKNLNAVKSPIFTPSSGRHEHGLLNLFHAMEGISHLHLLVVK EYEMPLYRKYWPNHIMLVLPGMFNNAGVGAARFLIKELSYHNLELERNRL EELGIKRQCVWPFIVMMDDSCVLWNIHSVQEPSSQPMEVGVSSKNVSLKT VLQHIEATPKIVHYAILGIQKWSSKLTSQSLKAPFSRCHVHDFILLNTDL TQNVQYDFNRYFCEDADFNLRTNSSGLLICRFNNFSLMKKHVQVGGQRDF IIKPKIMVSESLAPILPLQYICAPDSEHTLLAAPAQFLLEKFLQHASYKL FPKAIHNFRSPVLAIDCYLNIGPEVAICYISSRPHSSNVNCEGVFFSGLL LYLCDSFVGADLKKFKFLKGATLCVICQDRSSLRQTIVRLELEDEWQFRL RDEFQTANSSDDKPLYFLTGRHV
Reference
Dopunska literatura
Kategorija:Ljudski proteini Kategorija:Geni na hromosomu 18 Kategorija:Proteomika