E3 ubikvitin-protein ligaza UBR4 jest enzim koji je kod ljudi kodiran genom UBR4 sa hromosoma 1.
Aminokiselinska sekvenca Dužina polipeptidnog lanca je 5.183 aminokiselina, a molekulska težina 573.841 Da.
1020304050 MATSGGEEAAAAAPAPGTPATGADTTPGWEVAVRPLLSASYSAFEMKELP QLVASVIESESEILHHEKQYEPFYSSFVALSTHYITTVCSLIPRNQLQSV AAACKVLIEFSLLRLENPDEACAVSQKHLILLIKGLCTGCSRLDRTEIIT FTAMMKSAKLPQTVKTLSDVEDQKELASPVSPELRQKEVQMNFLNQLTSV FNPRTVASQPISTQTLVEGENDEQSSTDQASAIKTKNVFIAQNVASLQEL GGSEKLLRVCLNLPYFLRYINRFQDAVLANSFFIMPATVADATAVRNGFH SLVIDVTMALDTLSLPVLEPLNPSRLQDVTVLSLSCLYAGVSVATCMAIL HVGSAQQVRTGSTSSKEDDYESDAATIVQKCLEIYDMIGQAISSSRRAGG EHYQNFQLLGAWCLLNSLFLILNLSPTALADKGKEKDPLAALRVRDILSR TKEGVGSPKLGPGKGHQGFGVLSVILANHAIKLLTSLFQDLQVEALHKGW ETDGPPAALSIMAQSTSIQRIQRLIDSVPLMNLLLTLLSTSYRKACVLQR QRKGSMSSDASASTDSNTYYEDDFSSTEEDSSQDDDSEPILGQWFEETIS PSKEKAAPPPPPPPPPLESSPRVKSPSKQAPGEKGNILASRKDPELFLGL ASNILNFITSSMLNSRNNFIRNYLSVSLSEHHMATLASIIKEVDKDGLKG SSDEEFAAALYHFNHSLVTSDLQSPNLQNTLLQQLGVAPFSEGPWPLYIH PQSLSVLSRLLLIWQHKASAQGDPDVPECLKVWDRFLSTMKQNALQGVVP SETEDLNVEHLQMLLLIFHNFTETGRRAILSLFVQIIQELSVNMDAQMRF VPLILARLLLIFDYLLHQYSKAPVYLFEQVQHNLLSPPFGWASGSQDSNS RRATTPLYHGFKEVEENWSKHFSSDAVPHPRFYCVLSPEASEDDLNRLDS VACDVLFSKLVKYDELYAALTALLAAGSQLDTVRRKENKNVTALEACALQ YYFLILWRILGILPPSKTYINQLSMNSPEMSECDILHTLRWSSRLRISSY VNWIKDHLIKQGMKAEHASSLLELASTTKCSSVKYDVEIVEEYFARQISS FCSIDCTTILQLHEIPSLQSIYTLDAAISKVQVSLDEHFSKMAAETDPHK SSEITKNLLPATLQLIDTYASFTRAYLLQNFNEEGTTEKPSKEKLQGFAA VLAIGSSRCKANTLGPTLVQNLPSSVQTVCESWNNINTNEFPNIGSWRNA FANDTIPSESYISAVQAAHLGTLCSQSLPLAASLKHTLLSLVRLTGDLIV WSDEMNPPQVIRTLLPLLLESSTESVAEISSNSLERILGPAESDEFLARV YEKLITGCYNILANHADPNSGLDESILEECLQYLEKQLESSQARKAMEEF FSDSGELVQIMMATANENLSAKFCNRVLKFFTKLFQLTEKSPNPSLLHLC GSLAQLACVEPVRLQAWLTRMTTSPPKDSDQLDVIQENRQLLQLLTTYIV RENSQVGEGVCAVLLGTLTPMATEMLANGDGTGFPELMVVMATLASAGQG AGHLQLHNAAVDWLSRCKKYLSQKNVVEKLNANVMHGKHVMILECTCHIM SYLADVTNALSQSNGQGPSHLSVDGEERAIEVDSDWVEELAVEEEDSQAE DSDEDSLCNKLCTFTITQKEFMNQHWYHCHTCKMVDGVGVCTVCAKVCHK DHEISYAKYGSFFCDCGAKEDGSCLALVKRTPSSGMSSTMKESAFQSEPR ISESLVRHASTSSPADKAKVTISDGKVADEEKPKKSSLCRTVEGCREELQ NQANFSFAPLVLDMLNFLMDAIQTNFQQASAVGSSSRAQQALSELHTVEK AVEMTDQLMVPTLGSQEGAFENVRMNYSGDQGQTIRQLISAHVLRRVAMC VLSSPHGRRQHLAVSHEKGKITVLQLSALLKQADSSKRKLTLTRLASAPV PFTVLSLTGNPCKEDYLAVCGLKDCHVLTFSSSGSVSDHLVLHPQLATGN FIIKAVWLPGSQTELAIVTADFVKIYDLCVDALSPTFYFLLPSSKIRDVT FLFNEEGKNIIVIMSSAGYIYTQLMEEASSAQQGPFYVTNVLEINHEDLK DSNSQVAGGGVSVYYSHVLQMLFFSYCQGKSFAATISRTTLEVLQLFPIN IKSSNGGSKTSPALCQWSEVMNHPGLVCCVQQTTGVPLVVMVKPDTFLIQ EIKTLPAKAKIQDMVAIRHTACNEQQRTTMILLCEDGSLRIYMANVENTS YWLQPSLQPSSVISIMKPVRKRKTATITTRTSSQVTFPIDFFEHNQQLTD VEFGGNDLLQVYNAQQIKHRLNSTGMYVANTKPGGFTIEISNNNSTMVMT GMRIQIGTQAIERAPSYIEIFGRTMQLNLSRSRWFDFPFTREEALQADKK LNLFIGASVDPAGVTMIDAVKIYGKTKEQFGWPDEPPEEFPSASVSNICP SNLNQSNGTGDSDSAAPTTTSGTVLERLVVSSLEALESCFAVGPIIEKER NKNAAQELATLLLSLPAPASVQQQSKSLLASLHTSRSAYHSHKDQALLSK AVQCLNTSSKEGKDLDPEVFQRLVITARSIAIMRPNNLVHFTESKLPQME TEGMDEGKEPQKQLEGDCCSFITQLVNHFWKLHASKPKNAFLAPACLPGL THIEATVNALVDIIHGYCTCELDCINTASKIYMQMLLCPDPAVSFSCKQA LIRVLRPRNKRRHVTLPSSPRSNTPMGDKDDDDDDDADEKMQSSGIPNGG HIRQESQEQSEVDHGDFEMVSESMVLETAENVNNGNPSPLEALLAGAEGF PPMLDIPPDADDETMVELAIALSLQQDQQGSSSSALGLQSLGLSGQAPSS SSLDAGTLSDTTASAPASDDEGSTAATDGSTLRTSPADHGGSVGSESGGS AVDSVAGEHSVSGRSSAYGDATAEGHPAGPGSVSSSTGAISTTTGHQEGD GSEGEGEGETEGDVHTSNRLHMVRLMLLERLLQTLPQLRNVGGVRAIPYM QVILMLTTDLDGEDEKDKGALDNLLSQLIAELGMDKKDVSKKNERSALNE VHLVVMRLLSVFMSRTKSGSKSSICESSSLISSATAAALLSSGAVDYCLH VLKSLLEYWKSQQNDEEPVATSQLLKPHTTSSPPDMSPFFLRQYVKGHAA DVFEAYTQLLTEMVLRLPYQIKKITDTNSRIPPPVFDHSWFYFLSEYLMI QQTPFVRRQVRKLLLFICGSKEKYRQLRDLHTLDSHVRGIKKLLEEQGIF LRASVVTASSGSALQYDTLISLMEHLKACAEIAAQRTINWQKFCIKDDSV LYFLLQVSFLVDEGVSPVLLQLLSCALCGSKVLAALAASSGSSSASSSSA PVAASSGQATTQSKSSTKKSKKEEKEKEKDGETSGSQEDQLCTALVNQLN KFADKETLIQFLRCFLLESNSSSVRWQAHCLTLHIYRNSSKSQQELLLDL MWSIWPELPAYGRKAAQFVDLLGYFSLKTPQTEKKLKEYSQKAVEILRTQ NHILTNHPNSNIYNTLSGLVEFDGYYLESDPCLVCNNPEVPFCYIKLSSI KVDTRYTTTQQVVKLIGSHTISKVTVKIGDLKRTKMVRTINLYYNNRTVQ AIVELKNKPARWHKAKKVQLTPGQTEVKIDLPLPIVASNLMIEFADFYEN YQASTETLQCPRCSASVPANPGVCGNCGENVYQCHKCRSINYDEKDPFLC NACGFCKYARFDFMLYAKPCCAVDPIENEEDRKKAVSNINTLLDKADRVY HQLMGHRPQLENLLCKVNEAAPEKPQDDSGTAGGISSTSASVNRYILQLA QEYCGDCKNSFDELSKIIQKVFASRKELLEYDLQQREAATKSSRTSVQPT FTASQYRALSVLGCGHTSSTKCYGCASAVTEHCITLLRALATNPALRHIL VSQGLIRELFDYNLRRGAAAMREEVRQLMCLLTRDNPEATQQMNDLIIGK VSTALKGHWANPDLASSLQYEMLLLTDSISKEDSCWELRLRCALSLFLMA VNIKTPVVVENITLMCLRILQKLIKPPAPTSKKNKDVPVEALTTVKPYCN EIHAQAQLWLKRDPKASYDAWKKCLPIRGIDGNGKAPSKSELRHLYLTEK YVWRWKQFLSRRGKRTSPLDLKLGHNNWLRQVLFTPATQAARQAACTIVE ALATIPSRKQQVLDLLTSYLDELSIAGECAAEYLALYQKLITSAHWKVYL AARGVLPYVGNLITKEIARLLALEEATLSTDLQQGYALKSLTGLLSSFVE VESIKRHFKSRLVGTVLNGYLCLRKLVVQRTKLIDETQDMLLEMLEDMTT GTESETKAFMAVCIETAKRYNLDDYRTPVFIFERLCSIIYPEENEVTEFF VTLEKDPQQEDFLQGRMPGNPYSSNEPGIGPLMRDIKNKICQDCDLVALL EDDSGMELLVNNKIISLDLPVAEVYKKVWCTTNEGEPMRIVYRMRGLLGD ATEEFIESLDSTTDEEEDEEEVYKMAGVMAQCGGLECMLNRLAGIRDFKQ GRHLLTVLLKLFSYCVKVKVNRQQLVKLEMNTLNVMLGTLNLALVAEQES KDSGGAAVAEQVLSIMEIILDESNAEPLSEDKGNLLLTGDKDQLVMLLDQ INSTFVRSNPSVLQGLLRIIPYLSFGEVEKMQILVERFKPYCNFDKYDED HSGDDKVFLDCFCKIAAGIKNNSNGHQLKDLILQKGITQNALDYMKKHIP SAKNLDADIWKKFLSRPALPFILRLLRGLAIQHPGTQVLIGTDSIPNLHK LEQVSSDEGIGTLAENLLEALREHPDVNKKIDAARRETRAEKKRMAMAMR QKALGTLGMTTNEKGQVVTKTALLKQMEELIEEPGLTCCICREGYKFQPT KVLGIYTFTKRVALEEMENKPRKQQGYSTVSHFNIVHYDCHLAAVRLARG REEWESAALQNANTKCNGLLPVWGPHVPESAFATCLARHNTYLQECTGQR EPTYQLNIHDIKLLFLRFAMEQSFSADTGGGGRESNIHLIPYIIHTVLYV LNTTRATSREEKNLQGFLEQPKEKWVESAFEVDGPYYFTVLALHILPPEQ WRATRVEILRRLLVTSQARAVAPGGATRLTDKAVKDYSAYRSSLLFWALV DLIYNMFKKVPTSNTEGGWSCSLAEYIRHNDMPIYEAADKALKTFQEEFM PVETFSEFLDVAGLLSEITDPESFLKDLLNSVP
Reference
Dopunska literatura
Vanjski linkovi
Kategorija:Geni na hromosomu 1 Kategorija:Enzimi Kategorija:Ljudski proteini Kategorija:Proteomika